1216-01-9

Basic information

• Product Name: Pyridinium, 4-(methoxycarbonyl)-1-(phenylmethyl)-, iodide
• CAS NO: 1216-01-9
• Molecular Formula: C14H14NO2.I
• Molecular Weight: 355.175
• Mol File: 1216-01-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Pyridinium, 4-(methoxycarbonyl)-1-(phenylmethyl)-, iodide(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridinium, 4-(methoxycarbonyl)-1-(phenylmethyl)-, iodide(1216-01-9)
• EPA Substance Registry System: Pyridinium, 4-(methoxycarbonyl)-1-(phenylmethyl)-, iodide(1216-01-9)

Safety Data

• Hazardous Substances Data: 1216-01-9(Hazardous Substances Data)

Usage

General Description

Pyridinium, 4-(methoxycarbonyl)-1-(phenylmethyl)-, iodide is a chemical compound that is commonly used in organic synthesis as a reagent for various transformations. It is a quaternary ammonium salt containing a pyridinium ring with a phenylmethyl group and a methoxycarbonyl moiety attached to it. The iodide ion balances the positive charge on the pyridinium nitrogen. Pyridinium, 4-(methoxycarbonyl)-1-(phenylmethyl)-, iodide is often employed as a catalyst in reactions such as the formation of esters, amides, and other organic functional groups. Its unique structure and properties make it a versatile and valuable tool in the field of organic chemistry.

Upstream product

• 2459-09-8 4-pyridinecarboxylic acid, methyl ester 
• 100-44-7 benzyl chloride 

Downstream Products

• 80845-52-9 methyl 1-benzyl-2-(3-indolyl)-1,2,3,6-tetrahydropyridine-4-carboxylate 
• 80845-58-5 methyl 1-benzyl-1,2,3,6-tetrahydropyridine-4-carboxylate 
• 80845-48-3 methyl 1-benzyl-2-cyano-1,2,3,6-tetrahydropyridine-4-carboxylate 
• 80845-78-9 methyl 1-benzyl-2-cyano-3-<1-benzyl-4-(methoxycabonyl)-3-piperidyl>-1,2,3,6-tetrahydropyridine-4-carboxylate 

Relevant articles and documents

Synthetic Applications of 2-Cyano-1,2,3,6-tetrahydropyridines. Improved Synthesis of the Fundamental Tetracyclic Framework of Dasycarpidone

2-Cyano-1,2,3,6-tetrahydropyridines 2b-d, with a functionalized C-4 substituent, were prepared from the corresponding pyridinium salts by sodium borohydride reduction in the presence of sodium cyanide.Reaction of these 2-cyanotetrahydropyridines with indolylmagnesium iodide afforded 3-(1,2,3,6-tetrrahydro-2-pyridyl)indoles 3b-d.Alternatively, 3c and 3d were prepared in excellent yield by condensation of 2-cyanotetrahydropyridines 2c and 2d with indole in acetic acid medium.Deethyldasycarpidone was obtained from 3b in poor or moderate yields by three alternative procedures and from 3c in a three-step sequence.The preparation of deethyldasycarpidone from 2-cyanotetrahydropyridine 2c via the (tetrahydropyridyl)indole 3c constitutes an improved synthesis of this tetracyclic ring system.Similarly, 20-deethyl-4-demethyldasycarpidone was obtained from (tetrahydropyridyl)indole 3d.