1217296-42-8

Basic information

• Product Name: 8-(2-chlorophenyl)-1,5-naphthyrid-2(1H)-one
• Synonyms: 8-(2-chlorophenyl)-1,5-naphthyrid-2(1H)-one
• CAS NO: 1217296-42-8
• Molecular Weight: 256.691
• Mol File: 1217296-42-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8-(2-chlorophenyl)-1,5-naphthyrid-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 8-(2-chlorophenyl)-1,5-naphthyrid-2(1H)-one(1217296-42-8)
• EPA Substance Registry System: 8-(2-chlorophenyl)-1,5-naphthyrid-2(1H)-one(1217296-42-8)

Safety Data

• Hazardous Substances Data: 1217296-42-8(Hazardous Substances Data)

Upstream product

• 1217296-41-7 8-(2-chlorophenyl)-2-methoxynaphthyridine 
• 1211579-32-6 8-bromo-1,5-naphthyrid-2(1H)-one 
• 3900-89-8 2-Chlorobenzeneboronic acid 

Downstream Products

• 479-43-6 canthin-6-one 

Relevant articles and documents

Two-step total syntheses of Canthin-6-one alkaloids: New one-pot sequential Pd-catalyzed Suzuki-Miyaura coupling and Cu-catalyzed amidation reaction

Chemical Equation Presented Canthin-6-one (1) and nine analogues including the naturally occurring 9-methoxycanthin-6-one (2) and amaroridine (3) are prepared rapidly and in high yields via a convergent non-classical strategy that focuses on construction of the central ring B. The strategy relies on concomitant Pd-catalyzed Suzuki-Miyaura C-C coupling followed by a Cu-catalyzed C-N coupling that can be achieved either stepwise or in a new one-pot protocol starting from the appropriate 8-bromo-1,5-naphthyrldine.