1217458-19-9Relevant articles and documents
Enzymic disruption of N-aroyl-L-homoserine lactone-based quorum sensing
Momb, Jessica,Yoon, Dae-Wi,Fast, Walter
, p. 1535 - 1537 (2010)
(Chemical Equation Presented) Quorum-sensing molecules: A genetically encodable metallo-γ-lactonase from B. thuringiensis (AiiA) is shown to effectively quench N-aroyl-L-homoserine lactone-based signaling. Here it is reported that N-aroyl-HSLs are excellent substrates of AiiA, and that the broad substrate specificity of AiiA makes it a useful tool in the quenching of a wide variety of naturally occurring and coumaroyl-L-homoserine lactones (pC-HSLs).