121746-07-4

Basic information

• Product Name: N-benzoyl-N'-(3-cyano-4,5-dimethyl-2-thienyl)thiourea
• Synonyms: N-benzoyl-N'-(3-cyano-4,5-dimethyl-2-thienyl)thiourea
• CAS NO: 121746-07-4
• Molecular Formula: C₁₅H₁₃N₃OS₂
• Molecular Weight: 315.41322
• Mol File: 121746-07-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-benzoyl-N'-(3-cyano-4,5-dimethyl-2-thienyl)thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzoyl-N'-(3-cyano-4,5-dimethyl-2-thienyl)thiourea(121746-07-4)
• EPA Substance Registry System: N-benzoyl-N'-(3-cyano-4,5-dimethyl-2-thienyl)thiourea(121746-07-4)

Safety Data

• Hazardous Substances Data: 121746-07-4(Hazardous Substances Data)

Upstream product

• 4651-94-9 2-amino-4,5-dimethylthiophene-3-carbonitrile 
• 532-55-8 Benzoyl isothiocyanate 

Downstream Products

• 1160436-79-2 N-[3-(3-cyano-4,5-dimethyl-2-thienyl)-4-oxo-1,3-thiazolidin-2-ylidene]benzamide 
• 134866-01-6 [(4-amino-5,6-dimethylthieno[2,3-d]pyrimidin-2-yl)sulfanyl](phenyl)acetic acid 
• 1198355-34-8 5,6-dimethyl-2-[(2-phenylethyl)sulfanyl]thieno[2,3-d]pyrimidin-4-amine 

Relevant articles and documents

A Facile Synthesis of 2-Alkylthio-4-amino-thienopyrimidines

The reaction of 2-benzoylthioureidothiophene-3-carbonitriles D/8,9 with diluted NaOH yields 4-amino-thienopyrimidin-2(1H)-thiones E/10,11.Compounds D react in alkaline solution with various alkyl halides in one step to give 2-alkylthio-4-amino-thie

Analogs of a 4-aminothieno[2,3-d]pyrimidine lead (QB13) as modulators of P-glycoprotein substrate specificity

P-glycoprotein (P-gp) is an important factor in the development of multidrug resistance (MDR) in cancer cells. In literature reports, a thieno[2,3-d]pyrimidine (QB13) was described as P-gp modulator and opposed effects on the cell accumulation of distinct