121775-87-9

Basic information

• Product Name: methyl 2-(hydroxy(4-methoxyphenyl)methyl)but-3-enoate
• CAS NO: 121775-87-9
• Molecular Weight: 236.268
• Mol File: 121775-87-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl 2-(hydroxy(4-methoxyphenyl)methyl)but-3-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(hydroxy(4-methoxyphenyl)methyl)but-3-enoate(121775-87-9)
• EPA Substance Registry System: methyl 2-(hydroxy(4-methoxyphenyl)methyl)but-3-enoate(121775-87-9)

Safety Data

• Hazardous Substances Data: 121775-87-9(Hazardous Substances Data)

Upstream product

• 3724-55-8 methyl but-3-enoate 
• 123-11-5 4-methoxy-benzaldehyde 
• 1117-71-1 methyl-4-bromo-2-butenoate 
• 186581-53-3 diazomethane 
• 3724-65-0 2-butenoic acid 

Relevant articles and documents

Total regio- and diastereocontrol in the aldol reactions of dienolborinates

It is reported that appropriate dienolborinates can provide access to both diastereomers of 2-(hydroxymethyl)but-3-enoates through exclusive α-regiocontrol in a non-vinylogous pathway. Contrary to previous reports in which dialkylchloroboranes failed to enolize propanoates, acidity-enhanced but-3-enoates readily undergo enolization, offering unprecedented control over the formation of these valuable synthons. The first example of an aldol reaction in the presence of a phosphine-borane adduct is also reported.

Dienediolates from Unsaturated Carboxylic Acids. Reaction with para-Substituted Benzaldehydes. Electronic Effects on Regioselectivity

Regioselectivity α/γ ratios for addition of the lithium dienediolate of crotonic acid to para-substituted benzaldehydes are subject to small electronic effects when reactions are carried out at low temperature, but strong influence by substituents is observed on heating for 1 h at 60 deg C.A linear correlation is then found between regiochemical ratios and ?p parameters.Stereoselectivity RR/RS ratios (33:66 to 43:57) for α-adducts obtained in the cold do not depend on the substituents.