1217854-15-3 Usage
Description
(R)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one is a complex ketone derivative featuring a tertiary amine group, a methoxyphenyl group, and a methyl group attached to the ketone functional group. The (R)designation signifies the specific spatial arrangement of its substituents, which may contribute to its potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
(R)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one is used as a potential pharmaceutical compound for its unique structure and functional groups, which may offer novel therapeutic applications after further research and analysis.
Used in Organic Synthesis:
In the field of organic chemistry, (R)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one serves as a reagent that could be utilized in the synthesis of other complex organic molecules, taking advantage of its specific stereochemistry and functional groups.
Check Digit Verification of cas no
The CAS Registry Mumber 1217854-15-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,7,8,5 and 4 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1217854-15:
(9*1)+(8*2)+(7*1)+(6*7)+(5*8)+(4*5)+(3*4)+(2*1)+(1*5)=153
153 % 10 = 3
So 1217854-15-3 is a valid CAS Registry Number.
1217854-15-3Relevant articles and documents
Asymmetric Transfer Hydrogenation of α-Substituted-β-Keto Carbonitriles via Dynamic Kinetic Resolution
Wang, Fangyuan,Yang, Tilong,Wu, Ting,Zheng, Long-Sheng,Yin, Congcong,Shi, Yongjie,Ye, Xiang-Yu,Chen, Gen-Qiang,Zhang, Xumu
, p. 2477 - 2483 (2021/02/16)
A catalytic protocol for the enantio- and diastereoselective reduction of α-substituted-β-keto carbonitriles is described. The reaction involves a DKR-ATH process with the simultaneous construction of β-hydroxy carbonitrile scaffolds with two contiguous stereogenic centers. A wide range of α-substituted-β-keto carbonitriles were obtained in high yields (94%-98%) and excellent enantio- and diastereoselectivities (up to >99% ee, up to >99:1 dr). The origin of the diastereoselectivity was also rationalized by DFT calculations. Furthermore, this methodology offers rapid access to the pharmaceutical intermediates of Ipenoxazone and Tapentadol.
PREPARATION OF (2R,3R)-3-(3-METHOXYPHENYL)-N,N,2-TRIMETHYLPENTANAMINE
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Page/Page column 8, (2008/06/13)
The present invention relates to an improved process for the preparation of (2R,3R)-3- (3-methoxyphenyl)-N,N,2-trimethylpentanamine which is an intermediate for the preparation of the analgesic tapentadol.