121789-62-6

Basic information

• Product Name: 2-(3,5-Dichlor-2-hydroxyphenyl)-1H-pyrrol
• Synonyms: 2-(3,5-Dichlor-2-hydroxyphenyl)-1H-pyrrol
• CAS NO: 121789-62-6
• Molecular Weight: 228.078
• Mol File: 121789-62-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(3,5-Dichlor-2-hydroxyphenyl)-1H-pyrrol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,5-Dichlor-2-hydroxyphenyl)-1H-pyrrol(121789-62-6)
• EPA Substance Registry System: 2-(3,5-Dichlor-2-hydroxyphenyl)-1H-pyrrol(121789-62-6)

Safety Data

• Hazardous Substances Data: 121789-62-6(Hazardous Substances Data)

Upstream product

• 5213-08-1 3,5-dichloro-2-methoxybenzoyl chloride 
• 527-62-8 2,4-dichloro-6-aminophenol 
• 109-97-7 pyrrole 
• 64122-23-2 methyl 3,5-dichloro-2-methoxybenzoate 
• 22775-37-7 3,5-dichloro-2-methoxybenzoic acid 
• 69640-33-1 2-(3,5-dichloro-2-methoxyphenyl)-1H-pyrrole 
• 121789-29-5 1-(3,5-Dichlor-2-methoxyphenyl)-3-(1,3-dioxan-2-yl)-1-propanon 
• 121789-41-1 1-(3,5-Dichlor-2-methoxyphenyl)-1,4-butandion 

Downstream Products

• 69640-38-6 2,4-dichloro-6-(3,4,5-trichloro-1H-pyrrol-2-yl)phenol 

Relevant articles and documents

C–H Arylation of N-Heteroarenes under Metal-Free Conditions and its Application towards the Synthesis of Pentabromo- and Pentachloropseudilins

Herein, we are reporting metal-free conditions for radical initiation and direct C–H arylation of N-heteroarenes. Starting from aniline, the corresponding arenediazonium salt generated in situ is reduced to an aryl radical in the presence of chloropromazine hydrochloride, a new reagent for this application. The optimized procedures are mild, operationally simple, and are working successfully with more diverse substrates in comparison to reported methods. The optimized method is also employed for the synthesis of marine natural products Pentabromo- and Pentachloropseudilins (PBP/PCP). In the present study, we also validated the potential of the Pentachloropseudilin (PCP), thus synthesized, for inhibition of Myosin1 function in mammalian cells and confirmed that PCP phenocopies Myosin1c depletion in cells.