1218819-84-1

Basic information

• Product Name: 3-(4-methoxyphenethyl)-4-(3-methoxyphenyl)-1H-1,2,4-triazol-5(4H)-one
• CAS NO: 1218819-84-1
• Molecular Weight: 325.367
• Mol File: 1218819-84-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(4-methoxyphenethyl)-4-(3-methoxyphenyl)-1H-1,2,4-triazol-5(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-methoxyphenethyl)-4-(3-methoxyphenyl)-1H-1,2,4-triazol-5(4H)-one(1218819-84-1)
• EPA Substance Registry System: 3-(4-methoxyphenethyl)-4-(3-methoxyphenyl)-1H-1,2,4-triazol-5(4H)-one(1218819-84-1)

Safety Data

• Hazardous Substances Data: 1218819-84-1(Hazardous Substances Data)

Upstream product

• 890944-59-9 N-(3-methoxyphenyl)-2-(3-(4-methoxyphenyl)propanoyl)hydrazinecarboxamide 
• 121670-33-5 3-(4-methoxyphenyl)propionic acid hydrazide 
• 18908-07-1 3-methoxyphenyl isocyanate 
• 15823-04-8 methyl 3-(4-methoxyphenyl)propionate 

Relevant articles and documents

Synthesis, crystal structure and b-glucuronidase inhibition activity of some new hydrazinecarboxamides and their 1,2,4-triazole derivatives

A new series of hydrazinecarboxamides (5a-n), bearing various methoxyphenyl and methoxyphenethyl groups, was synthesized by condensation of corresponding acid hydrazides (3a-f) with methoxyphenylisocyanates (4a-c). Dehydrocyclization of hydrazinecarboxamides (5a-n) yielded corresponding methoxyphenyl and methoxyphenethyl substituted triazoles (6a-l) by refluxing in 2 N aqueous sodium hydroxide solution. All the synthesized compounds were screened for their b-glucuronidase inhibition activity. Compounds 5a, 5e, 5h, and 5l exhibited an excellent b-glucuronidase inhibitory activity as compared to the standard inhibitor. Springer Science+Business Media, LLC 2011.