121952-97-4Relevant articles and documents
Proapoptotic effects of novel thiazole derivative on human glioma cells
Finiuk, Nataliya,Klyuchivska, Olha,Ivasechko, Iryna,Hreniukh, Volodymyr,Ostapiuk, Yuriy,Shalai, Yaryna,Panchuk, Rostyslav,Matiychuk, Vasyl,Obushak, Mykola,Stoika, Rostyslav,Babsky, Andriy
, p. 27 - 37 (2019)
The aim of the present study was to investigate the antiproliferative and proapoptotic actions of N-(5-benzyl-1,3-thiazol-2-yl)-3,5-dimethyl-1-benzofuran-2-carboxamide derivative (compound 5) in glioma cells in comparison with the actions of temozolomide
Synthesis, structural characterization and thermal studies of a novel reagent 1-[(5-benzyl-1,3-thiazol-2-yl)diazenyl]naphthalene-2-ol
Tupys, Andrii,Kalembkiewicz, Jan,Ostapiuk, Yurii,Matiichuk, Vasyl,Tymoshuk, Oleksandr,Wo?nicka, El?bieta,Byczyński, ?ukasz
, p. 2233 - 2242 (2017)
A new thiazolylazo reagent 1-[(5-benzyl-1,3-thiazol-2-yl)diazenyl]naphthalene-2-ol has been synthesized via arylation of acrolein and further diazotization and diazocoupling with 2-naphthol. The chemical structure of the compound was confirmed by IR, NMR:
COMPOUNDS AND USES THEREOF
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Page/Page column 315-316, (2019/10/15)
The present invention features compounds useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.
Synthesis and antitumor activities of new n-(5-benzylthiazol-2-yl)-2-(heteryl-5-ylsulfanyl)-acetamides
Ostapiuk, Yu. V.,Frolov,Vasylyschyn, R. Ya.,Matiychuk
, p. 59 - 71 (2018/05/15)
Aim. Synthesis of a series of new N-(5-benzyl-thiazol-2-yl)-2-(heteryl-5-ylsulfanyl)-acetamides and study of their anticancer activity. Methods. Organic synthesis, analytical and spectral methods, pharmacological screening. Results. [2-chloro-N-(5-aryl-1,