1220100-84-4

Basic information

• Product Name: methyl 2-(2-aminophenyl)pyridine-4-carboxylate
• Synonyms: methyl 2-(2-aminophenyl)pyridine-4-carboxylate
• CAS NO: 1220100-84-4
• Molecular Weight: 228.25
• Mol File: 1220100-84-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2-(2-aminophenyl)pyridine-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(2-aminophenyl)pyridine-4-carboxylate(1220100-84-4)
• EPA Substance Registry System: methyl 2-(2-aminophenyl)pyridine-4-carboxylate(1220100-84-4)

Safety Data

• Hazardous Substances Data: 1220100-84-4(Hazardous Substances Data)

Upstream product

• 26156-48-9 methyl 2-bromoisonicotinate 
• 191171-55-8 2-anilineboronic acid pinacol ester 

Relevant articles and documents

Mechanism of C-F reductive elimination from palladium(IV) fluorides

The first systematic mechanism study of C-F reductive elimination from a transition metal complex is described. C-F bond formation from three different Pd(IV) fluoride complexes was mechanistically evaluated. The experimental data suggest that reductive elimination occurs from cationic Pd(IV) fluoride complexes via a dissociative mechanism. The ancillary pyridyl-sulfonamide ligand plays a crucial role for C-F reductive elimination, likely due to a K 3 coordination mode, in which an oxygen atom of the sulfonyl group coordinates to Pd. The pyridyl-sulfonamide can support Pd(IV) and has the appropriate geometry and electronic structure to induce reductive elimination.