1220452-71-0

Basic information

• Product Name: 3-(4-hydroxyphenyl)-6-methylchroman-4-one
• CAS NO: 1220452-71-0
• Molecular Weight: 254.285
• Mol File: 1220452-71-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(4-hydroxyphenyl)-6-methylchroman-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-hydroxyphenyl)-6-methylchroman-4-one(1220452-71-0)
• EPA Substance Registry System: 3-(4-hydroxyphenyl)-6-methylchroman-4-one(1220452-71-0)

Safety Data

• Hazardous Substances Data: 1220452-71-0(Hazardous Substances Data)

Upstream product

• 39513-75-2 6-methyl-4-chromanone 
• 106-41-2 4-bromo-phenol 

Relevant articles and documents

Palladium-catalyzed direct arylation of 4-chromanones: Selective synthesis of racemic isoflavanones and 3,3-diaryl-4-chromanones

For the first time, the synthesis of racemic isoflavanones has been achieved in satisfactory to good yields and with high selectivity by Pd-catalyzed direct C-3 arylation of 3-unsubstituted 4-chromanones with aryl bromides with the aid of a Pd2(dba)3/tBu 3PHBF4 catalyst system in the presence of KHCO3 as the base in a dioxane/water mixture (4:1). This catalyst system has also been employed in an unprecedented synthesis of 3,3-diaryl-4-chromanones through direct arylation of 4-chromanones in water.