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1220627-08-6

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1220627-08-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1220627-08-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,0,6,2 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1220627-08:
(9*1)+(8*2)+(7*2)+(6*0)+(5*6)+(4*2)+(3*7)+(2*0)+(1*8)=106
106 % 10 = 6
So 1220627-08-6 is a valid CAS Registry Number.

1220627-08-6Downstream Products

1220627-08-6Relevant articles and documents

Discovery of Narrow Spectrum Kinase Inhibitors: New Therapeutic Agents for the Treatment of COPD and Steroid-Resistant Asthma

Onions, Stuart T.,Ito, Kazuhiro,Charron, Catherine E.,Brown, Richard J.,Colucci, Marie,Frickel, Fritz,Hardy, George,Joly, Kevin,King-Underwood, John,Kizawa, Yasuo,Knowles, Ian,Murray, P. John,Novak, Andrew,Rani, Anjna,Rapeport, Garth,Smith, Alun,Strong, Peter,Taddei, David M.,Williams, Jonathan G.

, p. 1727 - 1746 (2016/03/25)

The discovery of a novel series of therapeutic agents that has been designed and optimized for treating chronic obstructive pulmonary disease is reported. The pharmacological strategy was based on the identification of compounds that inhibit a defined subset of kinase enzymes modulating inflammatory processes that would be effective against steroid refractory disease and exhibit a sustained duration of action after inhaled delivery.

NOVEL COMPOUNDS

-

, (2011/10/31)

There is provided inter alia a compound of formula (I) wherein R1, J, Ar, L, X, R3 and R4 are as defined in the specification, for use in the treatment of inflammatory disorders.

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