1220669-06-6Relevant articles and documents
Gram-Scale Solution-Phase Synthesis of Heptapeptide Side Chain of Teixobactin 1
Chandrasekhar, Srivari,Donikela, Sangeetha,Mainkar, Prathama S.,Nayani, Kiranmai,Nomula, Vishnuvardhan
, p. 2268 - 2272 (2019/12/11)
We report herein a scalable synthesis of linear heptapeptide side chain of the depsipeptide natural product teixobactin through solution phase. The synthesis of heptapeptide was achieved through an efficient coupling of suitably protected tripeptide and tetrapeptide comprising of three d-amino acids and four usual l-amino acid subunits.