1220889-26-8

Basic information

• Product Name: C₂₂H₁₇F₂NO
• Synonyms: C₂₂H₁₇F₂NO
• CAS NO: 1220889-26-8
• Molecular Weight: 349.38
• Mol File: 1220889-26-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₁₇F₂NO(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₁₇F₂NO(1220889-26-8)
• EPA Substance Registry System: C₂₂H₁₇F₂NO(1220889-26-8)

Safety Data

• Hazardous Substances Data: 1220889-26-8(Hazardous Substances Data)

Upstream product

• 1220889-25-7 C₁₄H₈BrF₂NO 

Relevant articles and documents

Exploration of a new series of PAR1 antagonists

Two series of new PAR1 antagonists have been identified. The first incorporates a cinnamoylpiperidine motif and the second a cinnamoylpyridine pattern. The synthesis, biological activity and structure-activity relationship of these compounds are presented. In each series, one analog showed potent in vivo antithrombotic activity in a rat AV shunt model, with up to 53% inhibition at 1.25 mpk iv for compound 30.