1220909-51-2

Basic information

• Product Name: C₁₇H₁₉FN₄O
• Synonyms: C₁₇H₁₉FN₄O
• CAS NO: 1220909-51-2
• Molecular Weight: 314.362
• Mol File: 1220909-51-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₉FN₄O(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₉FN₄O(1220909-51-2)
• EPA Substance Registry System: C₁₇H₁₉FN₄O(1220909-51-2)

Safety Data

• Hazardous Substances Data: 1220909-51-2(Hazardous Substances Data)

Upstream product

• 462-43-1 3-fluoropropane-1-ol 
• 1220909-57-8 C₁₄H₁₃ClN₄ 

Relevant articles and documents

Synthesis and in vitro evaluation of imidazo[1,2- b ]pyridazines as ligands for β-amyloid plaques

A series of imidazo[1,2-b]pyridazine derivatives were synthesized and evaluated for binding to amyloid plaques in vitro using synthetic aggregates of Aβ1?40. Binding affinities of these compounds were found to range from 11.0 to >1000 nM, depending on the various substitution patterns in the 6-position and 2-position. 2-(4′-Dimethylaminophenyl)-6- (methylthio)imidazo[1,2-b]pyridazine (4) showed high binding affinity (K i = 11.0 nM) and might be useful for the development of novel positron emission tomography radiotracers for imaging Aβ plaques.