1221177-03-2

Basic information

• Product Name: C₂₀H₂₀N₄O₂
• Synonyms: C₂₀H₂₀N₄O₂
• CAS NO: 1221177-03-2
• Molecular Weight: 348.404
• Mol File: 1221177-03-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: C₂₀H₂₀N₄O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₂₀N₄O₂(1221177-03-2)
• EPA Substance Registry System: C₂₀H₂₀N₄O₂(1221177-03-2)

Safety Data

• Hazardous Substances Data: 1221177-03-2(Hazardous Substances Data)

Upstream product

• 28144-70-9 anthranilic acid amide 
• 637-88-7 1,4-Cyclohexanedione 

Relevant articles and documents

Probing the catalytic activity of highly efficient sulfonic acid fabricated cobalt ferrite magnetic nanoparticles for the clean and scalable synthesis of dihydro, spiro and bis quinazolinones

An exceptionally productive, rapid, simple, and eco-friendly approach for the synthesis of 2,3-dihydroquinazolin-4(1H)-one has been developed utilizing acidic magnetically retrievable cobalt ferrite nanoparticles (CFNP@SO3H). Herein, we have demonstrated the synthesis of these profoundly demanding N-heterocyclic molecules within 3-10 min in excellent yields at room temperature using the environmentally benign solvent ethanol. Outstanding catalytic performance, ease of retrievability, high turnover frequency (TOF) values (197.13-403.23 h?1), admirable green chemistry metrices, such as theEfactor (0.10), reaction mass efficiency (RME) value (90.9%), carbon efficiency (100%) and atom economy (AE) value (92.6%), and reusability for up to six runs without a significant loss of activity, make the current methodology advantageous from an environmental, as well as industrial perspective.

Glycerol based ionic liquid with a boron core: A new highly efficient and reusable promoting medium for the synthesis of quinazolinones

A highly efficient and environmental benign procedure for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones via the condensation of carbonyl compounds with 2-aminobenzamide using a glycerol based ionic liquid with a boron core as a new and reusable promoting medium is described. A broad range of substrates including aldehydes and ketone were condensed with 2-aminobenzamide. All reactions are completed in short times and the products are obtained in good to excellent yields. The reaction medium could be recycled and reused several times without any loss of efficiency. Moreover, presented procedure has been applied successfully for the synthesis of some novel bis(pyrazolinone) derivatives.