1221186-57-7

Basic information

• Product Name: 2-vinyl-4-methyl-6-[(2-fluorophenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone
• Synonyms: 2-vinyl-4-methyl-6-[(2-fluorophenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone
• CAS NO: 1221186-57-7
• Molecular Weight: 339.393
• Mol File: 1221186-57-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-vinyl-4-methyl-6-[(2-fluorophenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-vinyl-4-methyl-6-[(2-fluorophenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone(1221186-57-7)
• EPA Substance Registry System: 2-vinyl-4-methyl-6-[(2-fluorophenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone(1221186-57-7)

Safety Data

• Hazardous Substances Data: 1221186-57-7(Hazardous Substances Data)

Upstream product

• 1221186-30-6 2-bromo-4-methyl-6-[(2-fluorophenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone 
• 75927-49-0 pinacol vinylboronate 

Downstream Products

• 1186660-58-1 2-ethyl-4-methyl-6-[(2-fluorophenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone 

Relevant articles and documents

ACTIVATORS OF HUMAN PYRUVATE KINASE

Disclosed are pyruvate kinase M2 activators, which are, bis sulfonamide piperazinyl compounds of Formula (I) and 2,4-disubstituted 4H-thieno[3,2-b]pyrrole-2-(substituted benzyl)pyridazin-3(2H)ones of Formula (II), wherein L and R1 to R16 are as defined herein, that are useful in treating a number of diseases that are treatable by the activation of PKM2, for example, cancer and anemia, Formulas (I); (II).