122181-85-5 Usage
General Description
1H-Pyrrole-2-carboxylic acid, 1-amino-, methyl ester (9CI) is a chemical compound that is also known as Methyl 2-amino-1H-pyrrole-2-carboxylate. It is a derivative of pyrrole, a five-membered aromatic ring compound, with a carboxylic acid and an amino group on adjacent carbon atoms. 1H-Pyrrole-2-carboxylicacid,1-amino-,methylester(9CI) is used in various chemical and pharmaceutical applications, including as a building block for the synthesis of other organic molecules. It has potential biological activity and may be used in the development of new drugs and pharmaceuticals. Additionally, it may also have uses in organic synthesis and material science.
Check Digit Verification of cas no
The CAS Registry Mumber 122181-85-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,1,8 and 1 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 122181-85:
(8*1)+(7*2)+(6*2)+(5*1)+(4*8)+(3*1)+(2*8)+(1*5)=95
95 % 10 = 5
So 122181-85-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H8N2O2/c1-10-6(9)5-3-2-4-8(5)7/h2-4H,7H2,1H3
122181-85-5Relevant articles and documents
Pyrrolotriazine compounds and applications thereof
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Paragraph 0094; 0097; 0099, (2020/05/01)
The invention belongs to the field of medical chemistry, and particularly relates to a class of lactam-based histone deacetylase inhibitors and a preparation method thereof, a pharmaceutical composition containing the histone deacetylase inhibitor, and applications of the inhibitors in drugs for preventing and/or treating diseases related to histone deacetylase activity out-of-control.
PYRROLOTRIAZINE INHIBITORS OF IRAK4 ACTIVITY
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Page/Page column 33, (2016/09/26)
The present invention relates to pyrrolotriazine inhibitors of IRAK4 of formula (I) and provides compositions comprising such inhibitors, as well as methods therewith for treating IRAK4-mediated or -associated conditions or diseases.
PYRROLOTRIAZINONE DERIVATIVES AS PI3K INHIBITORS
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Page/Page column 172, (2012/11/13)
New pyrrolotriazinone derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks).
