122253-24-1

Basic information

• Product Name: 3-Bromomethyl-2-(4-fluoro-phenyl)-4-isopropyl-6-phenyl-pyridine
• CAS NO: 122253-24-1
• Molecular Weight: 384.291
• Mol File: 122253-24-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Bromomethyl-2-(4-fluoro-phenyl)-4-isopropyl-6-phenyl-pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromomethyl-2-(4-fluoro-phenyl)-4-isopropyl-6-phenyl-pyridine(122253-24-1)
• EPA Substance Registry System: 3-Bromomethyl-2-(4-fluoro-phenyl)-4-isopropyl-6-phenyl-pyridine(122253-24-1)

Safety Data

• Hazardous Substances Data: 122253-24-1(Hazardous Substances Data)

Upstream product

• 122252-57-7 2-(4-Fluoro-benzoyl)-4-methyl-3-(2-oxo-2-phenyl-ethyl)-pentanoic acid methyl ester 
• 122252-71-5 2-(4-Fluoro-phenyl)-4-isopropyl-6-phenyl-nicotinic acid methyl ester 
• 63131-29-3 methyl 4-fluorobenzoyl acetate 
• 7316-69-0 1-phenyl-4-methyl-2-penten-1-one 
• 122253-01-4 2-(4-fluorophenyl)-4-(1-methylethyl)-6-phenyl-3-pyridinemethanol 

Downstream Products

• 123930-27-8 3-{(E)-2-[(2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-methoxy-tetrahydro-pyran-2-yl]-vinyl}-2-(4-fluoro-phenyl)-4-isopropyl-6-phenyl-pyridine 
• 122253-68-3 3-{(Z)-2-[(2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-methoxy-tetrahydro-pyran-2-yl]-vinyl}-2-(4-fluoro-phenyl)-4-isopropyl-6-phenyl-pyridine 
• 122254-11-9 (4R,6S)-4-(tert-Butyl-diphenyl-silanyloxy)-6-{(E)-2-[2-(4-fluoro-phenyl)-4-isopropyl-6-phenyl-pyridin-3-yl]-vinyl}-tetrahydro-pyran-2-one 
• 122253-89-8 (4R,6S)-4-(tert-Butyl-diphenyl-silanyloxy)-6-{(E)-2-[2-(4-fluoro-phenyl)-4-isopropyl-6-phenyl-pyridin-3-yl]-vinyl}-tetrahydro-pyran-2-ol 

Relevant articles and documents

Synthesis and Biological Activity of New HMG-CoA Reductase Inhibitors. 1. Lactones of Pyridine- and Pyrimidine-Substituted 3,5-Dihydroxy-6-heptenoic (-heptanoic) Acids

Lactones of pyridine- and pyrimidine-substituted 3,5-dihydroxy-6-heptenoic (-heptanoic) acids 2-4 have been synthesized.Extensive exploration of structure-activity relationships led to several compounds exceeding the inhibitory activity of mevinolin (1b)