1223-44-5

Basic information

• Product Name: 4-Nitrophenyl phenylacetate
• Synonyms: 4-Nitrophenyl phenylacetate;Benzeneacetic acid 4-nitrophenyl ester
• CAS NO: 1223-44-5
• Molecular Formula: C₁₄H₁₁NO₄
• Molecular Weight: 257.24144
• Mol File: 1223-44-5.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Nitrophenyl phenylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Nitrophenyl phenylacetate(1223-44-5)
• EPA Substance Registry System: 4-Nitrophenyl phenylacetate(1223-44-5)

Safety Data

• Hazardous Substances Data: 1223-44-5(Hazardous Substances Data)

Upstream product

• 100-02-7 4-nitro-phenol 
• 103-80-0 phenylacetyl chloride 
• 103-82-2 phenylacetic acid 

Downstream Products

• 621-06-7 2,N-diphenylacetamide 
• 14609-74-6 p-nitrophenolate 
• 1372996-49-0 (3S,4S)-3,6-diphenyl-4-(p-tolyl)-1-tosyl-3,4-dihydropyridin-2(1H)-one 
• 1372996-55-8 (3S,4S)-3,6-diphenyl-4-(thiophen-2-yl)-1-tosyl-3,4-dihydropyridin-2(1H)-one 
• 1380402-70-9 (3R,4R)-6-(4-chlorophenyl)-3,4-diphenyl-1-tosyl-3,4-dihydropyridin-2(1H)-one 
• 1372996-58-1 (3S,4S)-6-(4-chlorophenyl)-3,4-diphenyl-1-tosyl-3,4-dihydropyridin-2(1H)-one 
• 1372996-57-0 (3S,4S)-6-(3-bromophenyl)-3,4-diphenyl-1-tosyl-3,4-dihydropyridin-2(1H)-one 
• 1372996-51-4 (3S,4S)-4-(naphthalen-2-yl)-3,6-diphenyl-1-tosyl-3,4-dihydropyridin-2(1H)-one 
• 1380402-71-0 (3R,4R)-6-(4-methoxyphenyl)-3,4-diphenyl-1-tosyl-3,4-dihydropyridin-2(1H)-one 
• 1372996-59-2 (3S,4S)-6-(4-methoxyphenyl)-3,4-diphenyl-1-tosyl-3,4-dihydropyridin-2(1H)-one 

Relevant articles and documents

Enzyme-responsive amphiphilic PEG-dendron hybrids and their assembly into smart micellar nanocarriers

Enzyme-responsive micelles have great potential as drug delivery platforms due to the high selectivity of the activating enzymes. Here we report a highly modular design for the efficient and simple synthesis of amphiphilic block copolymers based on a line

Evaluating aryl esters as bench-stable C(1)-ammonium enolate precursors in catalytic, enantioselective Michael addition-lactonisations

An evaluation of a range of aryl, alkyl and vinyl esters as prospective C(1)-ammonium enolate precursors in enantioselective Michael addition-lactonisation processes with (E)-trifluoromethylenones using isothiourea catalysis is reported. Electron deficient aryl esters are required for reactivity, with 2,4,6-trichlorophenyl esters providing optimal product yields. Catalyst screening showed that tetramisole was the most effective isothiourea catalyst, giving the desired dihydropyranone product in excellent yield and stereoselectivity (up to 90 : 10 dr and 98 : 2 er). The scope and limitations of this process have been evaluated, with a range of diester products being generated after ring-opening with MeOH to give stereodefined dihydropyranones with excellent stereocontrol (10 examples, typically ～90 : 10 dr and >95 : 5 er).

Uniting C1-Ammonium Enolates and Transition Metal Electrophiles via Cooperative Catalysis: The Direct Asymmetric α-Allylation of Aryl Acetic Acid Esters

The direct, catalytic, asymmetric α-functionalization of acyclic esters constitutes a significant challenge in the area of asymmetric catalysis, particularly where the configurational integrity of the products is problematic. Through the unprecedented mer