122346-63-8

Basic information

• Product Name: (Z)-ascaridole
• CAS NO: 122346-63-8
• Molecular Weight: 168.236
• Mol File: 122346-63-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (Z)-ascaridole(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-ascaridole(122346-63-8)
• EPA Substance Registry System: (Z)-ascaridole(122346-63-8)

Safety Data

• Hazardous Substances Data: 122346-63-8(Hazardous Substances Data)

Usage

Description

(Z)-Ascaridole is a bicyclic monoterpene, a natural organic compound found in the essential oil of the Mexican tea plant. It has been recognized for its potent antimicrobial and antiparasitic properties, positioning it as a promising candidate for the development of new pharmaceuticals. (Z)-ascaridole's chemical structure and biological activities have garnered significant interest for further research and development within the medicinal chemistry field.

Uses

Used in Pharmaceutical Development:
(Z)-Ascaridole is used as a potential alternative treatment for parasitic infections due to its effectiveness against a wide range of pathogens, including bacteria, fungi, and parasites. Its potent antimicrobial and antiparasitic properties make it a valuable compound for the development of new pharmaceuticals to combat various infections.
Used in Antimicrobial Applications:
In the field of antimicrobial research, (Z)-ascaridole is utilized as an active agent to combat bacterial infections. Its potent antimicrobial properties allow it to be a viable option for treating and preventing bacterial diseases.
Used in Antiparasitic Applications:
(Z)-Ascaridole is also used as an antiparasitic agent, effective against various parasites. This application makes it a valuable tool in the treatment and prevention of parasitic infections, offering a potential alternative to conventional antiparasitic medications.
Used in Medicinal Chemistry Research:
Due to its unique chemical structure and biological activities, (Z)-ascaridole is used as a subject of study in medicinal chemistry. Researchers are interested in exploring its potential for further development and application in the creation of new drugs and therapies.

Upstream product

• 99-86-5 1-methyl-4-isopropyl-1,3-cyclohexadiene 

Downstream Products

• 1619-26-7 Pseudo-ascaridol 

Relevant articles and documents

Efficient and recyclable phthalocyanine-based sensitizers for photooxygenation reactions

Treatment of 4,5-bis(4-methoxycarbonylphenoxy) phthalonitrile with Zn(OAc)2·2H2O and 1,8-diazabicyclo[5.4.0]undec-7- ene in octan-1-ol or dodecan-1-ol led to base-promoted cyclotetramerization. Under these conditions, transesterification also occurred to give the corresponding zinc(II) octakis(4-alkoxycarbonylphenoxyphthalocyanines. These two macrocycles, together with another two pegylated silicon(IV) phthalocyanines, were found to be highly efficient sensitizers for the photooxygenation of a series of alkenes and 1-naphthol. In general, the zinc(II) analogues exhibit a higher photostability and can be recycled at least four times without a significant loss of activity. Georg Thieme Verlag Stuttgart.

Photooxygenations in a bubble column reactor

A novel column reactor was constructed and successfully applied to dye-sensitized photooxygenation reactions in aqueous alcohol solutions. The air flow pattern within the narrow glass column could be controlled via the size of the air inlet capillary. Using a 500 μm capillary, a slug flow pattern was realized which allowed for superior mass transfer and light transparency within a thin solvent layer. These features subsequently gave higher conversion rates and isolated yields.

Electron transfer-induced dehydrogenation reactions within methyl viologen-supported zeolite Na-Y under non-irradiative conditions

Methyl viologen-supported zeolite Na-Y is a unique and very efficient medium for carrying out electron transfer-induced reactions in the absence of an irradiation source (spontaneously). Several monoterpenes loaded within the supported zeolite are dehydrogenated to p-cymene. The reaction occurs even in the open air with formation of minor amounts of ascaridole depending on the substrate. It is proposed that the radical cations of the monoterpenes are formed by single electron transfer to Na-Y, with methyl viologen acting as a promoter.