1224432-15-8Relevant articles and documents
A novel class of antihyperlipidemic agents with low density lipoprotein receptor up-regulation via the adaptor protein autosomal recessive hypercholesterolemia
Asano, Shigehiro,Ban, Hitoshi,Tsuboya, Norie,Uno, Shinsaku,Kino, Kouichi,Ioriya, Katsuhisa,Kitano, Masafumi,Ueno, Yoshihide
experimental part, p. 3284 - 3295 (2010/09/05)
We have previously reported compound 2 as a inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) and up-regulator of the low density lipoprotein receptor (LDL-R) expression. In this study we focused on compound 2, a unique LDL-R up-regulator,