1224470-80-7Relevant articles and documents
Searching for multi-target antipsychotics: Discovery of orally active heterocyclic N-phenylpiperazine ligands of D2-like and 5-HT1A receptors
Neves, Gilda,Menegatti, Ricardo,Antonio, Camila B.,Grazziottin, Luiza R.,Vieira, Renan O.,Rates, Stela M.K.,No?l, Fran?ois,Barreiro, Eliezer J.,Fraga, Carlos A.M.
experimental part, p. 1925 - 1935 (2010/06/14)
We described herein the design, synthesis, and pharmacological evaluation of N-phenylpiperazine heterocyclic derivatives as multi-target compounds potentially useful for the treatment of schizophrenia. The isosteric replacement of the heterocyclic ring at