1225230-21-6Relevant articles and documents
Synthesis and evaluation of duocarmycin SA analogs incorporating the methyl 1,2,8,8a-tetrahydrocyclopropa[c]oxazolo[2,3-e]indol-4-one-6-carboxylate (COI) alkylation subunit
Boyle, Kristopher E.,MacMillan, Karen S.,Ellis, David A.,Lajiness, James P.,Robertson, William M.,Boger, Dale L.
supporting information; experimental part, p. 1854 - 1857 (2010/07/04)
The design, synthesis and evaluation of methyl 1,2,8,8a-tetrahydrocyclopropa[c]oxazolo[2,3-e]indol-4-one-6-carboxylate (COI) derivatives are detailed representing analogs of duocarmycin SA containing an oxazole replacement for the fused pyrrole found in t