1225232-81-4

Basic information

• Product Name: 3-(ethoxycarbonyl)-2-methyl-5-(5,5-pentamethylene-1,3,4-pentatrien-2-yl)-4,5-dihydrofuran
• Synonyms: 3-(ethoxycarbonyl)-2-methyl-5-(5,5-pentamethylene-1,3,4-pentatrien-2-yl)-4,5-dihydrofuran
• CAS NO: 1225232-81-4
• Molecular Weight: 288.387
• Mol File: 1225232-81-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(ethoxycarbonyl)-2-methyl-5-(5,5-pentamethylene-1,3,4-pentatrien-2-yl)-4,5-dihydrofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(ethoxycarbonyl)-2-methyl-5-(5,5-pentamethylene-1,3,4-pentatrien-2-yl)-4,5-dihydrofuran(1225232-81-4)
• EPA Substance Registry System: 3-(ethoxycarbonyl)-2-methyl-5-(5,5-pentamethylene-1,3,4-pentatrien-2-yl)-4,5-dihydrofuran(1225232-81-4)

Safety Data

• Hazardous Substances Data: 1225232-81-4(Hazardous Substances Data)

Upstream product

• 114707-16-3 ethyl 2-(buta-2,3-dienyl)-3-oxobutanoate 
• 61699-43-2 methyl 1,1-pentamethyleneprop-2-ynyl carbonate 

Relevant articles and documents

Palladium-catalyzed synthesis of 1,3,4-alkatrien-2-yldihydrofurans from 2,3-allenylacetylacetates and propargylic carbonates and their application to synthesize polysubstituted dihydrofurylcyclopentenones

An efficient route to 1,3,4-alkatrien-2-yldihydrofurans via a highly chemo- and regioselective palladium(0)-catalyzed coupling-cyclization reaction of 2-(2′,3′-allenyl)acetylacetates with propargylic carbonates was reported. The reaction proceeded smoothly under neutral conditions, affording the O-attacked five-membered products with a 1,3,4-trienyl substituent exclusively in good to excellent yields. The products can be efficiently applied to the synthesis of polysubstituted 2-(dihydrofuryl)cyclopentenone derivatives via a catalytic Pauson-Khand reaction under ambient conditions.