1225289-40-6

Basic information

• Product Name: 1-(3,3,3-trifluoropropynyl)-1-prop-2-ynyloxy-cyclohexane
• Synonyms: 1-(3,3,3-trifluoropropynyl)-1-prop-2-ynyloxy-cyclohexane
• CAS NO: 1225289-40-6
• Molecular Weight: 230.23
• Mol File: 1225289-40-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(3,3,3-trifluoropropynyl)-1-prop-2-ynyloxy-cyclohexane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,3,3-trifluoropropynyl)-1-prop-2-ynyloxy-cyclohexane(1225289-40-6)
• EPA Substance Registry System: 1-(3,3,3-trifluoropropynyl)-1-prop-2-ynyloxy-cyclohexane(1225289-40-6)

Safety Data

• Hazardous Substances Data: 1225289-40-6(Hazardous Substances Data)

Upstream product

• 96302-93-1 1-(3,3,3-trifluoro-1-propynyl)-1-cyclohexanol 
• 106-96-7 propargyl bromide 
• 108-94-1 cyclohexanone 

Downstream Products

• 1225289-59-7 5-trifluoromethyl-6,7-diphenyl-1,3-dihydroisobenzofuran-3-spiro-cyclohexane 

Relevant articles and documents

Practical Synthesis of α-Trifluoromethylated Pyridines Based on Regioselective Cobalt-Catalyzed [2+2+2] Cycloaddition using Trifluoromethylated Diynes with Nitriles

Regioselective cobalt-catalyzed [2+2+2] cycloaddition using fluorine-containing diynes with nitriles was described. Cycloaddition of fluorinated diynes with nitriles under the influence of CoCl2(phen), zinc bromide, and zinc dust in dichloroethane at 80 °C for 3 h took place smoothly, exclusively affording the corresponding α-fluoroalkylated pyridines in excellent yields. In addition, dinitriles as substrate were also found to be suitable for this reaction, giving the corresponding fluoroalkylated bipyridine derivatives in excellent yields. (Figure presented.).