1225384-36-0Relevant articles and documents
COMPOSITIONS AND METHODS FOR SILENCING DNAJB1-PRKACA FUSION GENE EXPRESSION
-
Page/Page column 128; 129, (2021/05/07)
The disclosure relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the DNAJB 1 -PRKAC A fusion gene, and methods of using such dsRNA compositions to alter (e.g., inhibit) expression of DNAJB 1 -PRKAC A fusion.
SERPINA1 IRNA COMPOSITIONS AND METHODS OF USE THEREOF
-
Paragraph 0392; 0395, (2019/01/04)
The invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the Serpina1 gene, and methods of using such RNAi agents to inhibit expression of Serpina1 and methods of treating subjects having a Serpina1 associated disease, such as a liver disorder.
COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENE
-
Page/Page column 146; 147; 148, (2017/04/11)
The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the ALAS1 gene, and methods of using such dsRNA compositions to alter (e.g., inhibit) expression of ALAS1.