1225532-89-7

Basic information

• Product Name: diisopropyl 3,3-difluorocyclobutane-1,1-dicarboxylate
• Synonyms: diisopropyl 3,3-difluorocyclobutane-1,1-dicarboxylate;1,1-bis(propan-2-yl) 3,3-difluorocyclobutane-1,1-dicarboxylate;Bis(isopropyl)3,3-difluorocyclobutane-1,1-dicarboxylate;Diisopropyl 3,3-difluorocyclobutane-1,1-dicarboxylate - D11464
• CAS NO: 1225532-89-7
• Molecular Formula: C12H18F2O4
• Molecular Weight: 264.2657264
• Mol File: 1225532-89-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 257.4±40.0 °C(Predicted)
• Appearance: /
• Density: 1.16±0.1 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: diisopropyl 3,3-difluorocyclobutane-1,1-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: diisopropyl 3,3-difluorocyclobutane-1,1-dicarboxylate(1225532-89-7)
• EPA Substance Registry System: diisopropyl 3,3-difluorocyclobutane-1,1-dicarboxylate(1225532-89-7)

Safety Data

• Hazardous Substances Data: 1225532-89-7(Hazardous Substances Data)

Usage

General Description

Diisopropyl 3,3-difluorocyclobutane-1,1-dicarboxylate is a chemical compound with the molecular formula C12H18F2O4. It is commonly used as a building block in the synthesis of pharmaceutical compounds and agrochemicals. This chemical is a colorless liquid that is highly stable and does not react readily with other substances. It is often used as a reagent in organic synthesis reactions due to its ability to form strong bonds with other molecules. Additionally, it is important to handle this compound with care, as it is toxic if ingested and can also cause irritation to the skin and eyes upon contact.

Upstream product

• 893724-10-2 dipropan-2-yl 3-oxocyclobutane-1,1-dicarboxylate 
• 115118-68-8 3,3-dimethoxycyclobutane-1,1-dicarboxylic acid diisopropyl ester 

Downstream Products

• 1225532-86-4 1-amino-3,3-difluorocyclobutane-1-carboxylic acid 

Relevant articles and documents

Multigram Synthesis of Advanced 6,6-Difluorospiro[3.3]heptane-Derived Building Blocks

A convenient methodology for constructing 6,6-difluorospiro[3.3]heptane scaffold – a conformationally restricted isoster of gem-difluorocycloalkanes – is developed. A large array of novel 2-mono- and 2,2-bifunctionalized difluorospiro[3.3]heptane building blocks was obtained through the convergent synthesis strategy using a common synthetic precursor – 1,1-bis(bromomethyl)-3,3-difluorocyclobutane. The target compounds and intermediates were prepared by short reaction sequences (6–10 steps) on a multigram scale (up to 0.47 kg).

COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS

The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.