1225789-07-0

Basic information

• Product Name: 1-(4-bromophenyl)-2-methylpentan-3-one
• Synonyms: 1-(4-bromophenyl)-2-methylpentan-3-one
• CAS NO: 1225789-07-0
• Molecular Weight: 255.155
• Mol File: 1225789-07-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(4-bromophenyl)-2-methylpentan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-bromophenyl)-2-methylpentan-3-one(1225789-07-0)
• EPA Substance Registry System: 1-(4-bromophenyl)-2-methylpentan-3-one(1225789-07-0)

Safety Data

• Hazardous Substances Data: 1225789-07-0(Hazardous Substances Data)

Upstream product

• 17422-12-7 methyl 2-methyl-3-oxopentanoate 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 96-22-0 pentan-3-one 

Relevant articles and documents

Formation, Alkylation, and Hydrolysis of Chiral Nonracemic N-Amino Cyclic Carbamate Hydrazones: An Approach to the Enantioselective α-Alkylation of Ketones

The α-alkylation of ketones is a fundamental synthetic transformation. The development of asymmetric variants of this reaction is important given that numerous natural products, drugs, and related compounds exist as α-functionalized ketones or derivatives thereof. We previously reported our preliminary studies on the development of a new enantioselective ketone α-alkylation procedure using N-amino cyclic carbamate (ACC) auxiliaries. In comparison to other auxiliary-based methods, ACC alkylation offers a number of advantages and is both highly enantioselective and high yielding. Herein, we provide a full account of our studies on the enantioselective ACC ketone α-alkylation method.