1226-52-4 Usage
Chemical Properties
Yellow Solid
Uses
A metabolite of Triamterne, a diuretic agent.
Check Digit Verification of cas no
The CAS Registry Mumber 1226-52-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,2 and 6 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1226-52:
(6*1)+(5*2)+(4*2)+(3*6)+(2*5)+(1*2)=54
54 % 10 = 4
So 1226-52-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H11N7O/c13-9-7(5-1-3-6(20)4-2-5)16-8-10(14)18-12(15)19-11(8)17-9/h1-4,20H,(H6,13,14,15,17,18,19)
1226-52-4Relevant articles and documents
On the diuretic and saluretic activity of p-hydroxytriamterene and methoxytriamterene
Vollmer,Mutschler,Voelger
, p. 529 - 530 (2007/10/02)
Applying i.v. the phase-I-metabolite of 2,4,7-triamino-6-phenylpteridine (triamterene), p-hydroxytriamterene, to rats, we found a strong natriuresis. This contradicts the investigation of a previous study which stated that p-hydroxytriamterene is essentially inactive. We think, these different results depend on the fact that probably oral application was employed without testing the absorption concerned.