1226600-39-0Relevant articles and documents
Oxidative Heck Reaction of Fluorinated Olefins with Arylboronic Acids by Palladium Catalysis
Li, Yang,Tu, Dong-Huai,Gu, Yu-Jie,Wang, Bo,Wang, Yao-Yu,Liu, Zhao-Tie,Liu, Zhong-Wen,Lu, Jian
, p. 4340 - 4343 (2015)
The palladium-catalyzed oxidative Heck reaction of 2,3,3,3-tetrafluoroprop-1-ene with various arylboronic acids was explored for the first time. This method provides a direct route to access (Z)-β-fluoro-β-(trifluoromethyl)styrenes with high stereoselectivity.
Novel efficient synthesis of β-fluoro-β-(trifluoromethyl)styrenes
Goldberg, Aleksey A.,Muzalevskiy, Vasiliy M.,Shastin, Aleksey V.,Balenkova, Elisabeth S.,Nenajdenko, Valentine G.
experimental part, p. 384 - 388 (2010/04/24)
CF3CFBr2 was employed in catalytic olefination reactions of aromatic aldehydes. In situ prepared hydrazones of aldehydes were transformed to β-fluoro-β-(trifluoromethyl)styrenes by reaction with CF3CFBr2 under CuCl catalysis. Based on this reaction, a novel stereoselective approach towards β-fluoro-β-(trifluoromethyl)styrenes was elaborated. Nucleophilic vinylic substitution of fluorine by secondary amines, thiolates and alkoxides in β-fluoro-β-(trifluoromethyl)styrenes was also tested.