122684-34-8 Usage
Description
3-Aminocarbonyl-1-Boc-pyrrolidine, also known as tert-Butyl 3-Carbamoylpyrrolidine-1-carboxylate, is an organic compound with the molecular formula C9H16N2O2. It is a derivative of pyrrolidine, a heterocyclic amine, and features a tert-butoxycarbonyl (Boc) protecting group and an aminocarbonyl functional group. 3-Aminocarbonyl-1-Boc-pyrrolidine is significant in synthetic chemistry and pharmaceutical applications due to its unique structural features and reactivity.
Uses
Used in Pharmaceutical Industry:
3-Aminocarbonyl-1-Boc-pyrrolidine is used as an intermediate in the synthesis of various pharmaceutical compounds for [application reason]. Its unique structure allows for the development of novel drugs with potential therapeutic applications.
Used in Chemical Synthesis:
In the field of chemical synthesis, 3-Aminocarbonyl-1-Boc-pyrrolidine is used as a building block for the creation of complex organic molecules. Its versatile functional groups enable it to participate in a wide range of chemical reactions, making it a valuable compound for the synthesis of various organic compounds.
Used in Preparation and Sulfuration of 1,2,4-Thiadiazoles:
3-Aminocarbonyl-1-Boc-pyrrolidine is used as a key compound in the preparation and sulfuration of 1,2,4-thiadiazoles. These heterocyclic compounds have a wide range of applications, including pharmaceuticals, agrochemicals, and materials science. The use of 3-Aminocarbonyl-1-Boc-pyrrolidine in this process allows for the efficient synthesis of these important compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 122684-34-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,6,8 and 4 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 122684-34:
(8*1)+(7*2)+(6*2)+(5*6)+(4*8)+(3*4)+(2*3)+(1*4)=118
118 % 10 = 8
So 122684-34-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H18N2O3/c1-10(2,3)15-9(14)12-5-4-7(6-12)8(11)13/h7H,4-6H2,1-3H3,(H2,11,13)
122684-34-8Relevant articles and documents
General Ser/Thr Kinases Pharmacophore Approach for Selective Kinase Inhibitors Search as Exemplified by Design of Potent and Selective Aurora A Inhibitors
Vasilevich, Natalya I.,Aksenova, Elena A.,Kazyulkin, Denis N.,Afanasyev, Ilya I.
, p. 54 - 65 (2016)
A general pharmachophore model for various types of Ser/Thr kinases was developed. Search for the molecules fitting to this pharmacophore among ASINEX proprietary library revealed a number of compounds, which were tested and appeared to possess some activity against several Ser/Thr kinases such as Aurora A, Aurora B and Haspin. The possibility of performing the fine-tuning of the general Ser/Thr pharmacophore to desired types of kinase to get active and selective inhibitors was exemplified by Aurora A kinase. As a result, several hits in 3–5?nm range of activity against Aurora A kinase with rather good selectivity and ADME properties were obtained.
BENZIMIDAZOLE AND AZA-BENZIMIDAZOLE CARBOXAMIDES
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Page/Page column 44, (2010/05/14)
This invention provides compounds of Formula I which are PAFR antagonists: I and the pharmaceutically acceptable salts thereof. The compounds are useful for treating PAF-mediated disorders, and can be used in methods for treating atherosclerosis and preve
Synthesis and muscarinic activities of 1,2,4-thiadiazoles
MacLeod,Baker,Freedman,Patel,Merchant,Roe,Saunders
, p. 2052 - 2059 (2007/10/02)
A series of novel 1,2,4-thiadiazoles bearing a mono- or bicyclic amine at C5 were prepared. Quinuclidine and 1-azabicyclo[2.2.1]heptane derivatives were synthesized by reaction of the lithium enolate of the 3-methoxycarbonyl compounds followed by ester hy