1226985-26-7Relevant articles and documents
Regio- And Enantioselective Iridium-Catalyzed Amination of Alkyl-Substituted Allylic Acetates with Secondary Amines
Jung, Woo-Ok,Yoo, Minjin,Migliozzi, Madyson M.,Zbieg, Jason R.,Stivala, Craig E.,Krische, Michael J.
supporting information, p. 441 - 445 (2021/12/27)
Robust air-stable cyclometalated π-allyliridium C,O-benzoates modified by (S)-tol-BINAP catalyze the reaction of secondary aliphatic amines with racemic alkyl-substituted allylic acetates to furnish products of allylic amination with high levels of enantioselectivity. Complete branched regioselectivities were observed despite the formation of more highly substituted C-N bonds.
Stereoselective total synthesis of seimatopolide a
Bhunia, Nisith,Das, Biswanath
, p. 1633 - 1642 (2014/01/17)
Stereoselective total synthesis of the naturally occurring bioactive macrolide, seimatopolide A has been achieved starting from commercially available (+)-diethyl tartrate. Chelation-controlled Grignard reaction, Yamaguchi esterification, ring closing cross metathesis and CBS reduction reactions are involved as key steps.
Nickel-catalyzed allylic substitution of simple alkenes
Matsubara, Ryosuke,Jamison, Timothy F.
supporting information; experimental part, p. 1860 - 1875 (2012/02/02)
This report describes a nickel-catalyzed allylic substitution process of simple alkenes whereby an important structural motif, a 1,4-diene, was prepared. The key to success is the use of an appropriate nickel-phosphine complex and a stoichiometric amount of silyl triflate. Reactions of 1-alkyl-substituted alkenes consistently provided 1,1-disubstituted alkenes with high selectivity. Insight into the reaction mechanism as well as miscellaneous application of the developed catalytic process is also documented.
