1227009-32-6

Basic information

• Product Name: reserpine
• Synonyms: reserpine
• CAS NO: 1227009-32-6
• Molecular Weight: 646.737
• Mol File: 1227009-32-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: reserpine(CAS DataBase Reference)
• NIST Chemistry Reference: reserpine(1227009-32-6)
• EPA Substance Registry System: reserpine(1227009-32-6)

Safety Data

• Hazardous Substances Data: 1227009-32-6(Hazardous Substances Data)

Upstream product

• 50-55-5 reserpine 
• 106-96-7 propargyl bromide 

Downstream Products

• 1227009-38-2 C₇₂H₈₂N₄O₁₈ 
• 1227009-41-7 C₇₉H₉₆N₁₀O₂₀ 

Relevant articles and documents

Two versatile and parallel approaches to highly symmetrical open and closed natural product-based structures

Two parallel approaches for preparing diverse and highly symmetrical homohybrids derived from a series of mono- and diterpenes, steroids, and alkaloids are reported. Both procedures are based on the mono-addition of bis(alkynyl) dilithium reagents to natural products having a carbonyl group to produce the corresponding al-kynyl derivatives. The Glaser-Hay Cu-promoted homocoupling of these al-kynyl natural product mono-adducts as well as the Huisgen Cu-catalyzed azide-alkyne cycloaddition (CuAAC) reaction resulted in the synthesis of ste-roid-, terpene-, and alkaloid-based ho-mohybrid derivatives incorporating di-verse spacers to join the natural product scaffolds. Straightforward entries to novel closed highly symmetrical and complex estrone-based macrocyclic and cage architectures by means of the Glaser-Eglinton homocoupling and the CuAAC reaction have been devised.