1227053-83-9Relevant articles and documents
The B(C6F5)3-Catalyzed Tandem Meinwald Rearrangement-Reductive Amination
Tiddens, Martine R.,Klein Gebbink, Robertus J. M.,Otte, Matthias
supporting information, p. 3714 - 3717 (2016/08/16)
A system of three coupled catalytic cycles enabling the one-pot transformation of epoxides to amines via Meinwald rearrangement, imine condensation, and imine reduction is described. This assisted tandem catalysis is catalyzed by B(C6F5)3 resulting in the first tandem Meinwald rearrangement-reductive amination protocol. The reaction proceeds in nondried solvents and yields β-functionalized amines. In particular, β-diarylamines are obtained in high yields.
A commercially available tantalum catalyst for the highly regioselective intermolecular hydroaminoalkylation of styrenes
Doerfler, Jaika,Doye, Sven
, p. 2790 - 2797 (2014/05/06)
The C-C bond-forming catalytic hydroaminoalkylation of terminal alkenes or styrenes enables a direct and 100 % atom-efficient synthesis of amines and can generally result in the formation of two regioisomers, the branched and the linear product. Herein, we report that high-yielding intermolecular hydroaminoalkylation reactions of styrenes can be achieved with excellent regioselectivities in the presence of the commercially available homoleptic catalyst pentakis(dimethylamino)tantalum. In all cases, the branched regioisomer is formed almost exclusively. Highly regioselective intermolecular hydroaminoalkylation reactions of styrenes are achieved in the presence of the commercially available homoleptic catalyst [Ta(NMe2)5]. The process activates the α-C-H bonds of N-methylanilines and 1,2,3,4-tetrahydroquinoline and gives access to the corresponding branched hydroaminoalkylation products in good-to-excellent yields. Copyright
