1227053-90-8

Basic information

• Product Name: N-(3-(2,4-dimethylphenyl)propyl)aniline
• Synonyms: N-(3-(2,4-dimethylphenyl)propyl)aniline
• CAS NO: 1227053-90-8
• Molecular Weight: 239.36
• Mol File: 1227053-90-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(3-(2,4-dimethylphenyl)propyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-(2,4-dimethylphenyl)propyl)aniline(1227053-90-8)
• EPA Substance Registry System: N-(3-(2,4-dimethylphenyl)propyl)aniline(1227053-90-8)

Safety Data

• Hazardous Substances Data: 1227053-90-8(Hazardous Substances Data)

Upstream product

• 3422-01-3 tert-butyl phenylcarbamate 
• 62-53-3 aniline 
• 28131-24-0 tert-butyl N-methyl-N-(phenyl)carbamate 
• 2234-20-0 2,4-dimethylstyrene 
• 100-61-8 N-methylaniline 

Relevant articles and documents

A 2,6-bis(phenylamino)pyridinato titanium catalyst for the highly regioselective hydroaminoalkylation of styrenes and 1,3-butadienes

The C-C bond forming catalytic hydroaminoalkylation of terminal alkenes, 1,3-dienes, or styrenes allows a direct and highly atom efficient (100 %) synthesis of amines which can result in the formation of two regioisomers, the linear and the branched product. We present a new titanium catalyst with 2,6-bis(phenylamino)pyridinato ligands for intermolecular hydroaminoalkylation reactions of styrenes and 1-phenyl-1,3-butadienes that delivers the corresponding linear hydroaminoalkylation products with excellent regioselectivities. Linear progress: A new Ti complex with 2,6-bis(phenylamino) pyridinato ligands catalyzes highly regioselective hydroaminoalkylation reactions of styrenes. The process that directly gives access to the corresponding linear hydroaminoalkylation products offers a new and flexible synthetic approach towards pharmaceutically important 3-arylpropylamines. It is also possible to convert (E)-1-phenyl-1,3-butadienes into the corresponding linear products.

[Ind2TiMe2]: A catalyst for the hydroaminomethylation of alkenes and styrenes

(Chemical Equation Presentation) Metal-catalyzed hydroaminomethylations of styrenes, which take place by C-H bond activation, can be achieved in the presence of the catalyst [Ind2TiMe2] (Ind = η5-indenyl). Corresponding reactions of l-alkenes with N-methylanilines performed at temperatures between 80°C and 105°C usually take place with regioselectivities of better than 99:1 in favor of the branched product.