1227718-79-7

Basic information

• Product Name: (Z)-3-(1-methylcyclohexyl)acrylonitrile
• Synonyms: (Z)-3-(1-methylcyclohexyl)acrylonitrile
• CAS NO: 1227718-79-7
• Molecular Weight: 149.236
• Mol File: 1227718-79-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (Z)-3-(1-methylcyclohexyl)acrylonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-3-(1-methylcyclohexyl)acrylonitrile(1227718-79-7)
• EPA Substance Registry System: (Z)-3-(1-methylcyclohexyl)acrylonitrile(1227718-79-7)

Safety Data

• Hazardous Substances Data: 1227718-79-7(Hazardous Substances Data)

Upstream product

• 6140-64-3 1-methylcyclohexanecarbaldehyde 
• 1428990-72-0 C₂₂H₂₈NO₃P 
• 75-05-8 acetonitrile 

Relevant articles and documents

Highly Z-selective synthesis of a,b-unsaturated nitriles using the Horner-Wadsworth-Emmons reaction

A new HWE reagent, (o-tBuC6H4O)2P(O)CH2CN (2e), reacts with various types of aldehydes to give Z-a,bunsaturated nitriles with 86% to >99% Z-selectivity. Especially, the reaction of 2e with bulkier aldehydes, both aromatic and aliphatic, gave the Z-olefins with extremely high selectivity. The combination of t-BuOK and 18-crown-6 (1 equiv) is the base of choice for aromatic aldehydes and t-BuOK is generally the base of choice for aliphatic aldehydes.