122778-27-2

Basic information

• Product Name: 2-Methyl-malonic acid mono-[(1R,2R,5S)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl] ester
• CAS NO: 122778-27-2
• Molecular Weight: 332.44
• Mol File: 122778-27-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Methyl-malonic acid mono-[(1R,2R,5S)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl] ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-malonic acid mono-[(1R,2R,5S)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl] ester(122778-27-2)
• EPA Substance Registry System: 2-Methyl-malonic acid mono-[(1R,2R,5S)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl] ester(122778-27-2)

Safety Data

• Hazardous Substances Data: 122778-27-2(Hazardous Substances Data)

Upstream product

• 516-05-2 methyl-propanedioic acid 
• 65253-04-5 (-)-8-phenylmenthol 

Downstream Products

• 130562-73-1 methyl (1R,3R,4S)-8-phenyl-p-menthan-3-yl methylmalonate 
• 123463-77-4 (1R,3R,4S)-8-phenyl-p-menthan-3-yl hydrogen allyl(methyl)malonate 
• 123463-82-1 (1R,3R,4S)-8-phenyl-p-menthan-3-yl hydrogen 2-methoxybenzyl(methyl)malonate 
• 123463-82-1 (R)-2-(2-Methoxy-benzyl)-2-methyl-malonic acid mono-[(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl] ester 
• 134279-57-5 (S)-2-(2-Methoxy-benzyl)-2-methyl-malonic acid mono-[(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl] ester 
• 123463-78-5 (1R,3R,4S)-8-phenyl-p-menthan-3-yl hydrogen benzyl(methyl)malonate 
• 123463-78-5 (R)-2-Benzyl-2-methyl-malonic acid mono-[(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl] ester 
• 134279-53-1 (S)-2-Benzyl-2-methyl-malonic acid mono-[(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl] ester 
• 123463-81-0 (R)-2-(4-Methoxy-benzyl)-2-methyl-malonic acid mono-[(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl] ester 
• 134279-56-4 (S)-2-(4-Methoxy-benzyl)-2-methyl-malonic acid mono-[(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl] ester 
• 123463-75-2 (1R,3R,4S)-8-phenyl-p-menthan-3-yl hydrogen ethyl(methyl)malonate 
• 123463-75-2 (R)-2-Ethyl-2-methyl-malonic acid mono-[(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl] ester 
• 123463-83-2 (S)-2-Ethyl-2-methyl-malonic acid mono-[(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl] ester 
• 134279-44-0 (1R,3R,4S)-8-phenyl-p-menthan-3-yl (2'S)-2'-benzyloxycarbonylamino-2'-methyl-3'-phenylpropanoate 

Relevant articles and documents

Asymmetric Syntheses of Chiral Propane-1,3-diols Starting from Malonic Acid

Syntheses of chiral intermediates having one tertiary asymmetric centre were carried out via chiral half-esters of monoalkylmalonic acids.The menthyl half-ester of ethylmalonic acid afforded a single diastereoisomer through crystallisation-induced asymmetric transformation (second-order asymmertic transformation).Furthermore enantioselective preparation of unsymmertical propane-1,3-diol derivatives was achieved by the use of 8-phenylmenthyl half-esters.