1228451-69-1

Basic information

• Product Name: 6-(4-aminophenyl)-N-methyl-1H-indazole-3-carboxamide
• Synonyms: 6-(4-aminophenyl)-N-methyl-1H-indazole-3-carboxamide
• CAS NO: 1228451-69-1
• Molecular Weight: 266.302
• Mol File: 1228451-69-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-(4-aminophenyl)-N-methyl-1H-indazole-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(4-aminophenyl)-N-methyl-1H-indazole-3-carboxamide(1228451-69-1)
• EPA Substance Registry System: 6-(4-aminophenyl)-N-methyl-1H-indazole-3-carboxamide(1228451-69-1)

Safety Data

• Hazardous Substances Data: 1228451-69-1(Hazardous Substances Data)

Upstream product

• 1228451-61-3 1-tert-butyl 3-ethyl-6-(4-nitrophenyl)-1H-indazole-1,3-dicarboxylate 
• 1228451-59-9 1-tert-butyl 3-ethyl 6-bromo-1H-indazole-1,3-dicarboxylate 
• 885272-94-6 ethyl 6-bromo-1H-indazole-3-carboxylate 
• 660823-36-9 6-bromo-1H-indazole-3-carboxylic acid 
• 6326-79-0 6-bromoisatin 
• 1228451-67-9 N-methyl-6-(4-nitrophenyl)-1H-indazole-3-carboxamide 

Downstream Products

• 1228450-67-6 N-methyl-6-(4-(pyridazine-4-carboxamido)phenyl)-1H-indazole-3-carboxamide 

Relevant articles and documents

NOVEL INDAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS PROTEIN KINASE INHIBITORS FOR PROLIFERATIVE DISEASES TREATMENT, AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AS AN ACTIVE INGREDIENT

Disclosed are novel indazole derivatives represented by the following Chemical Formula 1 or pharmaceutically acceptable salts, hydrates or solvates thereof, and pharmaceutical compositions for the prevention or treatment of proliferative diseases, containing the same as an active ingredient. Having potent inhibitory effect against protein kinase, such as b-raf, KDR, Fms, Tie2, SAPK2a and Ret, inducing diseases caused by abnormal cell proliferation, the novel indazole derivatives can be used for the prevention or treatment of diseases caused by abnormal cell proliferation.