1228657-94-0

Basic information

• Product Name: C₁₃H₁₈ClNO₃
• Synonyms: C₁₃H₁₈ClNO₃
• CAS NO: 1228657-94-0
• Molecular Weight: 271.744
• Mol File: 1228657-94-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₃H₁₈ClNO₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₁₈ClNO₃(1228657-94-0)
• EPA Substance Registry System: C₁₃H₁₈ClNO₃(1228657-94-0)

Safety Data

• Hazardous Substances Data: 1228657-94-0(Hazardous Substances Data)

Upstream product

• 70946-18-8 N,N-diethyl-3,4-dimethoxybenzamide 

Downstream Products

• 5417-17-4 2-chloro-3,4-dimethoxybenzaldehyde 

Relevant articles and documents

A practical in situ generation of the schwartz reagent. reduction of tertiary amides to aldehydes and hydrozirconation

A new, highly efficient in situ protocol (Cp2ZrCl2/LiAlH(OBu-t)3) is described for the generation of the Schwartz reagent which provides a convenient method for the amide to aldehyde reduction and the regioselective hydrozirconation-iodination of alkynes and alkenes. Highlighted are chemoselective reductions of benzamides derived by directed ortho metalation (DoM) chemistry, allowing the synthesis of valuable 1,2,3-substituted benzaldehydes. The single-step, three-component process proceeds in a very short reaction time, shows excellent functional group compatibility, and uses inexpensive and long-storage stable reducing reagents.