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1228694-82-3

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1228694-82-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1228694-82-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,8,6,9 and 4 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1228694-82:
(9*1)+(8*2)+(7*2)+(6*8)+(5*6)+(4*9)+(3*4)+(2*8)+(1*2)=183
183 % 10 = 3
So 1228694-82-3 is a valid CAS Registry Number.

1228694-82-3Downstream Products

1228694-82-3Relevant articles and documents

Novel Chlorogenic Acid Derivatives and Composition for Treating Inflammatory Disease Comprising the Same

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Paragraph 0246; 0247; 0248; 0249, (2017/08/02)

The present invention relates to a novel chlorogenic acid derivative compound having anti-inflammatory activities and an anti-inflammatory composition comprising the same as an active ingredient. The chlorogenic acid derivative compound of the present invention inhibits overproduction of nitrogen oxide (NO) induced by treating LPS in macrophage. The chlorogenic acid derivative compound of the present invention suppresses activation of NF-κB which is a signal transmission-mediated transcription factor significant in an oxidative stress and inflammation-promoting path. The chlorogenic acid derivative compound of the present invention can be developed as medicine for various inflammatory diseases by inhibiting overproduction of nitrogen oxide and activation of NF-κB.

Synthesis and biological evaluation of caffeic acid derivatives as potent inhibitors of α-MSH-stimulated melanogenesis

Jo, Hyeju,Choi, Minho,Sim, Jaeuk,Viji, Mayavan,Li, Siyuan,Lee, Young Hee,Kim, Youngsoo,Seo, Seung-Yong,Zhou, Yuanyuan,Lee, Kiho,Kim, Wun-Jae,Hong, Jin Tae,Lee, Heesoon,Jung, Jae-Kyung

supporting information, p. 3374 - 3377 (2017/07/07)

We have disclosed our effort to develop caffeic acid derivatives as potent and non-toxic inhibitors of α-MSH-stimulated melanogenesis to treat pigmentation disorders and skin medication including a cosmetic skin-whitening agent. The SAR studies revealed t

Synthesis, structure and structure-activity relationship analysis of caffeic acid amides as potential antimicrobials

Fu, Jie,Cheng, Kui,Zhang, Zhi-ming,Fang, Rui-qin,Zhu, Hai-liang

experimental part, p. 2638 - 2643 (2010/07/09)

A series of caffeic acid amides 1-23 were synthesized and nine of which (13-17, 19-21 and 23) were reported for the first time. The chemical structures of these compounds were confirmed by means of 1H NMR, ESI MS and elemental analyses. Compound 15 was determined by single-crystal X-ray diffraction analysis. All of the compounds were assayed for antibacterial (Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens and Staphylococcus aureus) and antifungal (Aspergillus niger, Candida albicans and Trichophyton rubrum) activities by MTT method. Compounds 10-12, 15, 18 and 21 showed considerable antibacterial activities against B. subtilis with MICs of 7.95, 6.25, 3.89, 1.18, 3.12 and 15.5?μg/mL, respectively. Structure-activity relationship analysis disclosed that caffeic acid anilides with electron-donating groups at p-position of benzene ring have better inhibitory activities.

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