122888-36-2

Basic information

• Product Name: (6aR,9S,10aR)-9-(3,3-Diethyl-ureido)-7-methyl-6,6a,7,8,9,10-hexahydro-4H-indolo[4,3-fg]quinoline-10a-carboxylic acid phenylamide
• CAS NO: 122888-36-2
• Molecular Weight: 459.591
• Mol File: 122888-36-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (6aR,9S,10aR)-9-(3,3-Diethyl-ureido)-7-methyl-6,6a,7,8,9,10-hexahydro-4H-indolo[4,3-fg]quinoline-10a-carboxylic acid phenylamide(CAS DataBase Reference)
• NIST Chemistry Reference: (6aR,9S,10aR)-9-(3,3-Diethyl-ureido)-7-methyl-6,6a,7,8,9,10-hexahydro-4H-indolo[4,3-fg]quinoline-10a-carboxylic acid phenylamide(122888-36-2)
• EPA Substance Registry System: (6aR,9S,10aR)-9-(3,3-Diethyl-ureido)-7-methyl-6,6a,7,8,9,10-hexahydro-4H-indolo[4,3-fg]quinoline-10a-carboxylic acid phenylamide(122888-36-2)

Safety Data

• Hazardous Substances Data: 122888-36-2(Hazardous Substances Data)

Upstream product

• 37686-84-3 terguride 
• 115087-39-3 3-[(6aR,9S,10aR)-4-(tert-Butyl-dimethyl-silanyl)-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-yl]-1,1-diethyl-urea 
• 122923-19-7 3-[(6aR,9S,10aR)-4-(tert-Butyl-dimethyl-silanyl)-10a-formyl-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-yl]-1,1-diethyl-urea 

Relevant articles and documents

STRIKING INFLUENCE OF THE REACTION CONDITIONS ON THE STEREOSELECTIVITY IN ELECTROPHILIC SUBSTITUTION OF A 10-LITHIO-ERGOLINYL-UREA

The regioselectivity of the deprotonation of the 8α-ergolinyl-urea 1 (terguride) depends on the substituent at the indole nitrogen.A tert.-butyl-dimethylsilyl (TBDMS) protecting group facilitates the removal of the angular benzylic proton in position 10.The reaction of the 10-lithio compound 5 with electrophiles affords cis or trans fused products, depending on reagent and reaction conditions.