1228897-40-2Relevant articles and documents
Synthetic route optimization of PF-00868554, an HCV polymerase inhibitor in clinical evaluation
Johnson, Sarah,Drowns, Matt,Tatlock, John,Linton, Angelica,Gonzalez, Javier,Hoffman, Robert,Jewell, Tanya,Patel, Leena,Blazel, Julie,Tang, Mingnam,Li, Hui
scheme or table, p. 796 - 800 (2010/06/13)
This paper describes the optimization efforts to establish an enabling synthesis to provide multigram quantity of PF-00868554, an HCV polymerase inhibitor currently in phase II clinical evaluations.