1228928-25-3

Basic information

• Product Name: C₂₃H₂₃ClN₂O₂
• CAS NO: 1228928-25-3
• Molecular Weight: 394.901
• Mol File: 1228928-25-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₃H₂₃ClN₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₂₃ClN₂O₂(1228928-25-3)
• EPA Substance Registry System: C₂₃H₂₃ClN₂O₂(1228928-25-3)

Safety Data

• Hazardous Substances Data: 1228928-25-3(Hazardous Substances Data)

Upstream product

• 1228928-23-1 C₁₆H₁₇NO₃ 
• 7149-75-9 3-methyl-4-chloroaniline 

Relevant articles and documents

N -Alkyl-octahydroisoquinolin-1-one-8-carboxamides: Selective and nonbasic ?-opioid receptor ligands

Herein, we report that N-alkyl-octahydroisoquinolin-1-one-8-carboxamides are a novel class of readily synthesized, selective ?-opioid receptor (KOR) ligands. A striking feature of this class of compounds is the absence of any basic nitrogen atoms. Many of these compounds have demonstrated exclusive affinity for the KOR over not only the ?-opioid receptor and the ?-opioid receptor but also 38 other G protein-coupled receptor targets. The general binding affinity of this class of compounds for the KOR combined with a streamlined route for analogue synthesis provide strong motivation for pursuing this interesting new scaffold as a basis toward new probes targeting the KOR.