1228934-52-8 Usage
Description
(4S)-6-2-[(2R)-2-(3,5-dimethylbenzyl)piperidin-1-yl]-2-oxoethyl-4-(1H-indazol-3-ylmethyl)-1-phenyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-5(6H)-one is a complex chiral molecule with a benzodiazepine backbone and a triazolobenzodiazepine core structure. It features an indazole moiety, a phenyl group, and a piperidine ring, with stereocenters at the 4th and 2nd positions. The chemical structure indicates potential pharmaceutical activity, which may include anxiolytic or neuroprotective properties, although further research is necessary to confirm its specific characteristics and therapeutic applications.
Uses
Used in Pharmaceutical Industry:
(4S)-6-2-[(2R)-2-(3,5-dimethylbenzyl)piperidin-1-yl]-2-oxoethyl-4-(1H-indazol-3-ylmethyl)-1-phenyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-5(6H)-one is used as a potential anxiolytic or neuroprotective agent due to its complex chemical structure and the presence of a benzodiazepine backbone, which is commonly associated with such activities. Further research is required to validate its efficacy and safety in this application.
Used in Research and Development:
In the field of medicinal chemistry and drug discovery, this compound serves as a valuable research tool for understanding the structure-activity relationships of benzodiazepines and their derivatives. It can be used to explore new therapeutic avenues and develop novel drugs targeting the central nervous system.
Check Digit Verification of cas no
The CAS Registry Mumber 1228934-52-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,8,9,3 and 4 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1228934-52:
(9*1)+(8*2)+(7*2)+(6*8)+(5*9)+(4*3)+(3*4)+(2*5)+(1*2)=168
168 % 10 = 8
So 1228934-52-8 is a valid CAS Registry Number.
1228934-52-8Relevant articles and documents
Discovery of new piperidine amide triazolobenzodiazepinones as intestinal-selective CCK1 receptor agonists
Cameron, Kimberly O.,Beretta, Elena E.,Chen, Yue,Chu-Moyer, Margaret,Fernando, Dilinie,Gao, Hua,Kohrt, Jeffrey,Lavergne, Sophie,Jardine, Paul Da Silva,Guzman-Perez, Angel,Hoth, Christopher,Perry, David A.,Hadcock, John R.,Gautreau, Denise,Makowski, Michael,Perez, Sylvie,Polivkova, Jana,Rogers, Lucy,Scott, Dennis O.,Swick, Andrew G.,Thiede, Lucinda,Trebino, Catherine E.,Trilles, Richard V.,Wilmowski, Julie,Zhang, Yingxin
, p. 2943 - 2947 (2012/06/04)
New cholecystokinin-1 receptor (CCK1R) agonist 'triggers' were identified using iterative library synthesis. Structural activity relationship studies led to the discovery of compound 10e, a potent CCK1R agonist that demonstrated robust weight loss in a di
