123016-51-3

Basic information

• Product Name: 2,3,4,6-TETRAFLUOROBENZOYL CHLORIDE
• Synonyms: 2,3,4,6-TETRAFLUOROBENZOYL CHLORIDE;Benzoyl chloride, 2,3,4,6-tetrafluoro- (9CI)
• CAS NO: 123016-51-3
• Molecular Formula: C₇HClF₄O
• Molecular Weight: 212.53
• EINECS: -0
• Product Categories: ACIDHALIDE
• Mol File: 123016-51-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 94-97°C 61mm
• Flash Point: 94-97°C/61mm
• Appearance: /
• Density: 1.601g/cm³
• Vapor Pressure: 2.64mmHg at 25°C
• Refractive Index: 1.4700
• Sensitive: Moisture Sensitive
• BRN: 6398940
• CAS DataBase Reference: 2,3,4,6-TETRAFLUOROBENZOYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4,6-TETRAFLUOROBENZOYL CHLORIDE(123016-51-3)
• EPA Substance Registry System: 2,3,4,6-TETRAFLUOROBENZOYL CHLORIDE(123016-51-3)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN3265
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 123016-51-3(Hazardous Substances Data)

Usage

General Description

2,3,4,6-Tetrafluorobenzoyl chloride is a chemical compound with the molecular formula C7H2ClF4O. It is a colorless liquid that is widely used in the pharmaceutical and agrochemical industries as a key building block for the synthesis of various chemical compounds. It is a versatile intermediate in the production of insecticides, herbicides, and pharmaceuticals. 2,3,4,6-Tetrafluorobenzoyl chloride is a highly reactive compound and is often used in the synthesis of complex organic molecules. It is also used as a reagent in organic synthesis and as a precursor in the production of dyes and pigments. Due to its reactivity and potential health hazards, it is important to handle this compound with caution and use proper safety measures during its handling and storage.

InChI:InChI=1/C7HClF4O/c8-7(13)4-2(9)1-3(10)5(11)6(4)12/h1H

Upstream product

• 1551-39-9 2,4,5,6-tetrafluoroisophthalic acid 
• 32890-92-9 2,3,4,6-tetrafluorobenzoic acid 

Downstream Products

• 123016-52-4 ethyl 2,3,4,6-tetrafluorobenzoylacetate 
• 53001-70-0 2,4,5,6-tetrafluorobenzyl alcohol 
• 1109138-77-3 N-(2-chloroethyl)-2-(2,3,4,6-tetrafluorophenyl)acid amide 
• 174312-99-3 5-Benzylamino-8-chloro-1-cyclopropyl-7-fluoro-6-nitro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester 
• 127625-07-4 5-Benzylamino-8-chloro-1-cyclopropyl-7-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester 
• 123016-54-6 ethyl 2-(2,3,4,6-tetrafluorobenzoyl)-3-cyclopropylacrylate 
• 133434-01-2 diethyl 2,3,4,6-tetrafluorobenzoylmalonate 

Relevant articles and documents

QUINOLIN-4-ONE AND 4(1H)-CINNOLINONE COMPOUNDS AND METHODS OF USING SAME

The present disclosure relates to quinolin-4-one and 4(1H)-cinnolinone compounds and methods of using them to induce self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into tissue cells.

Imidazo- and triazoloquinolones as antibacterial agents. Synthesis and structure-activity relationships

4,5-Disubstituted 6-cyclopropyl-6,9-dihydro-9-oxo-1H-imidazo- (30-32) and triazolo[4,5-f]quinoline-8-carboxylic acids (33-35) were synthesized starting from 5,6-diaminoquinolones 25. The imidazoquinolones 30-32 were equal or superior to the corresponding triazoloquinolone analogues 33-35 in in vitro antibacterial activity. As for the C-5 substituents, a fluorine atom was the most favorable of the three groups, H, F, and Cl. Among the compounds prepared, 4-(cyclic amino)-5-fluoro-imidazoquinolones 31a-d showed potent and well-balanced antibacterial activity against both gram-positive and gram- negative bacteria. Structure-activity relationships for the C-4 substituents (cyclic amino groups) were also examined in detail.