1231233-11-6Relevant articles and documents
Synthesis of chiral bifunctional (Thio)urea n-heterocyclic carbenes
Brand, Jonathan P.,Siles, José Ignacio Osuna,Waser, Jér?me
supporting information; experimental part, p. 881 - 884 (2010/07/10)
The rapid and modular synthesis of the first bifunctional N-heterocyclic carbenes bearing a (thio)urea moiety as H-bond donor group was reported. Different analogues could be accessed in seven steps from cheap (S)-pyroglutamic acid in good overall yields (14-30%). The synthesized carbenes were active catalysts in the benzoin reaction. Georg Thieme Verlag Stuttgart - New York.