123151-45-1

Basic information

• Product Name: Phenol, 3-methoxy-2-(1-methylethyl)-
• CAS NO: 123151-45-1
• Molecular Formula: C10H14O2
• Molecular Weight: 166.22
• Mol File: 123151-45-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Phenol, 3-methoxy-2-(1-methylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 3-methoxy-2-(1-methylethyl)-(123151-45-1)
• EPA Substance Registry System: Phenol, 3-methoxy-2-(1-methylethyl)-(123151-45-1)

Safety Data

• Hazardous Substances Data: 123151-45-1(Hazardous Substances Data)

Upstream product

• 16700-61-1 1,3-dimethoxy-2-(1-methylethyl)benzene 
• 16929-70-7 1,3-dimethoxy-2-(1-hydroxy-1-methylethyl)benzene 
• 151-10-0 1,3-Dimethoxybenzene 
• 2040-04-2 2,6-dimethoxyacetophenone 
• 865305-63-1 2-(1-hydroxy-1-methyl-ethyl)-3-methoxy-phenol 

Downstream Products

• 123151-46-2 2-methoxy-3-isopropyl-1,4-benzoquinone 
• 935254-94-7 4-(2-isopropyl-3-methoxyphenoxy)benzonitrile 

Relevant articles and documents

NOVEL THYROMIMETICS

Compounds are provided having the structure of Formula (I) or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope, or salt thereof, wherein R1, R2, X1, X2, Y1, and Y2 are as defined herein. Such compounds function as thyromimetics and have utility for treating diseases such as neurodegenerative disorders and fibrotic diseases. Pharmaceutical compositions containing such compounds are also provided, as are methods of their use and preparation.

Methods of using diaminopyrimidine P2X3 and P2X2/3 receptor modulators for treatment of respiratory and gastrointestinal diseases

Methods for treating respiratory and gastrointestinal diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein D, X, Y, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein.

A New General Synthetic Approach to Diterpenes: Application to Syntheses of (+ -)-Taxodione and (+ -)-Royleanone.

High-pressure Diels - Alder reactions of 1,3,3-trimethyl-2-vinyl-1-cyclohexenes 3a,b,i with substituted 1,4-benzoquinones afford, in good yield, highly functionalized tricyclic ring systems which are found in many classes of naturally occuring terpenes.Notably, the reactions of 3a are highly regio- and stereoselective.Efficient, formal syntheses of antitumor diterpenes (+ -)-taxodione and (+ -)-royleanone are reported, which demonstrate the practical application of this new strategy for the preparation of varied terpene systems.Of particular interest is that the high-pressure reactions are accelerated by mild Lewis acids and the regio- and stereoselectivity of these reactions is also improved under the combined high-pressure / Lewis acid conditions in comparison to the high-pressure conditions alone.Indeed, in the reaction of 3a with 2-methoxy-5-methyl-1,4-benzoquinone, ZnBr2 is required to effect the Diels-Alder reaction even at 12 kbar, and endo adduct 12c is formed stereoselectively in 90percent yield.In contrast, low-temperature Ti(IV)-catalyzed reactions of diene 3a with methoxy-substituted 1,4-benzoquinones at atmospheric pressure regioselectively produce dihydrobenzofurans 19 and 20, apparently via alkylation of the quinone Ti(IV) complex by the diene followed by the ring closure.