123183-97-1

Basic information

• Product Name: 1-(3-Methoxy-phenyl)-pentane-1,4-dione
• Synonyms: 1-(3-Methoxy-phenyl)-pentane-1,4-dione
• CAS NO: 123183-97-1
• Molecular Weight: 206.241
• Mol File: 123183-97-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(3-Methoxy-phenyl)-pentane-1,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-Methoxy-phenyl)-pentane-1,4-dione(123183-97-1)
• EPA Substance Registry System: 1-(3-Methoxy-phenyl)-pentane-1,4-dione(123183-97-1)

Safety Data

• Hazardous Substances Data: 123183-97-1(Hazardous Substances Data)

Upstream product

• 598-32-3 2-hydroxy-3-butene 
• 766-85-8 3-methoxy-1-iodobenzene 
• 201230-82-2 carbon monoxide 
• 51594-60-6 1-(3-methoxyphenyl)prop-2-en-1-one 
• 75-07-0 acetaldehyde 

Downstream Products

• 123185-32-0 (4R,6R)-4-Hydroxy-6-{2-[2-(3-methoxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one 
• 123185-33-1 (4R,6R)-4-Hydroxy-6-{2-[2-(3-hydroxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one 
• 123184-62-3 3-[2-(3-Methoxy-phenyl)-5-methyl-pyrrol-1-yl]-propionaldehyde 

Relevant articles and documents

Development of a Palladium-Catalyzed Carbonylative Coupling Strategy to 1,4-Diketones

We report on a three-component palladium-catalyzed coupling strategy for accessing a wide range of 1,4-diketones, which represent important precursors to heterocycles. Our method relies on a carbonylative Heck reaction employing substituted allylic alcohols, aryl iodides, and carbon monoxide. The reaction conditions are mild and do not require high CO pressure, and a wide functional group tolerance is revealed, providing the desired 1,4-diketones in moderate to good yields. Furthermore, the methodology is adaptable to the selective installment of 13C-carbon isotopes at either one or both of the carbonyl positions.