123185-91-1

Basic information

• Product Name: cis-(4R,6S)-2,2-dimethyl-6-formyl-1,3-dioxane-4-acetic acid
• Synonyms: cis-(4R,6S)-2,2-dimethyl-6-formyl-1,3-dioxane-4-acetic acid
• CAS NO: 123185-91-1
• Molecular Weight: 202.207
• Mol File: 123185-91-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: cis-(4R,6S)-2,2-dimethyl-6-formyl-1,3-dioxane-4-acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: cis-(4R,6S)-2,2-dimethyl-6-formyl-1,3-dioxane-4-acetic acid(123185-91-1)
• EPA Substance Registry System: cis-(4R,6S)-2,2-dimethyl-6-formyl-1,3-dioxane-4-acetic acid(123185-91-1)

Safety Data

• Hazardous Substances Data: 123185-91-1(Hazardous Substances Data)

Downstream Products

• 118845-89-9 cis-(4R,6S)-6-<4,4-bis(4-fluorophenyl)-3-(1-methyl-1H-tetrazol-5-yl)-1,3-butadienyl>-2,2-dimethyl-1,3-dioxane-4-acetic acid 
• 118918-05-1 trans-(4R,6S)-6-[4,4-bis(4-fluorophenyl)-3-(1-methyl-1H-tetrazol-5-yl)-1,3-butadienyl]-tetrahydro-4-hydroxy-2H-pyran-2-one 
• 129785-03-1 (E)-(3R,5S)-9,9-Bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoic acid 
• 130320-56-8 BMY-21950 

Relevant articles and documents

Antihypercholesterolemic tetrazole compounds

Compounds of the formula STR1 wherein R1 and R4 each are independently hydrogen, halogen, C1-4 alkyl, C1-4 alkoxy, or trifluoromethyl; R2, R3, R5 and R6 each are independently hydrogen, halogen C1-4 alkyl or C1-4 alkoxy; tet is STR2 n is an integer of from 0 to 2, inclusive; A is STR3 R7 is hydrogen, C1-4 alkyl, C1-4 alkoxy(lower) alkyl or (2-methoxyethoxy)methyl; X is --OH or =O; and R8 is hydrogen, a hydrolyzable ester group or a cation to form a non-toxic pharmaceutically acceptable salt, are novel antihypercholesterolemic agents which inhibit cholesterol biosynthesis. Intermediates and processes for their preparation are disclosed.

Antihypercholesterolemic tetrazol-1-yl compounds

Compounds of the formula STR1 wherein R1, R2, R3, and R4 each are independently hydrogen, halogen, C1-4 alkyl, C1-4 alkoxy or trifluoromethyl; R is hydrogen, C1-4 alkyl or phenyl; A is STR2 R5 is hydrogen, a hydrolyzable ester group or a cation to form a non-toxic pharmaceutically acceptable salt, are novel antihypercholesterolemic agents which inhibit cholesterol biosynethesis. Intermediates and processes for their preparation are disclosed.